A Computer Model of Mid-Flexion Instability in a Balanced Total Knee Arthroplasty

Some patients have mid-flexion instability despite stability at 0° and 90° of flexion. This study aims to determine the effects of total knee arthroplasty (TKA) stability while changing femur implant size and position.

A computational analysis was performed simulating knee flexion of posterior stabilized (PS) and cruciate retaining (CR) TKA designs. Deviations from the ideal TKA implant position were simulated by adjusting tibiofemoral proximal-distal position and femur anterior-posterior position as well as implant size. Forces in ligaments connecting the femur and tibia were collected. Total tibiofemoral ligament load for mid-knee flexion of 15°-75° was analyzed vs proximal-distal implant position, implant size, implant design, and knee flexion for PS and CR knees. Posterior cruciate ligament load was also analyzed for CR knees.

Total tibiofemoral ligament load was significantly reduced by a more proximal tibiofemoral and anterior femur position (P < .001). Implant size did not have a significant effect on tibiofemoral ligament load (P > .1). Implant design and knee flexion significantly influenced total tibiofemoral ligament load (P < .001), but the interactions with implant proximal-distal position were not significant (P > .2), indicating that implant proximal-distal position had a similar effect across the 15°-75° knee flexion range for both studied PS and CR implant designs.

PS and CR TKA can be well-balanced at 0° and 90° knee flexion and have instability in mid-flexion. Elevating the joint line and shifting the femur anteriorly can cause the knee to be too loose in mid-flexion.