Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intervention in acute myocardial infarction.

W Kübler, G Schuler, F Schwarz

    The American Journal of Cardiology
    |July 15, 1987
    PubMed
    Summary

    Early reperfusion therapy is crucial for reducing myocardial infarction. Prompt treatment, ideally within 3-5 hours, improves outcomes by restoring oxygen supply and minimizing heart muscle damage.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The efficacy of injectable bone fillers for alveolar ridge preservation: a microcomputed tomographic analysis.

    International journal of implant dentistry·2026
    Same author

    Predicting adverse events for risk stratification of chemotherapy based stem cell mobilization in multiple myeloma.

    NPJ digital medicine·2026
    Same author

    Clinical Performance of Immediately Restored, Surface Modified Two-Piece Zirconia Implants. A Prospective Case Series.

    Clinical oral implants research·2025
    Same author

    Removal of fiber posts using conventional versus guided endodontics: a comparative study of dentin loss and complications.

    Clinical oral investigations·2024
    Same author

    Evaluation of ECG-Gated, High-Pitch Thoracoabdominal Angiographies With Dual-Source Photon-Counting Detector Computed Tomography.

    Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists·2024
    Same author

    Clinical outcomes following a combined vertical and horizontal alveolar ridge augmentation and two-stage implant placement using either autogenous tooth roots or autogenous bone blocks.

    Clinical implant dentistry and related research·2024

    Area of Science:

    • Cardiology
    • Cardiovascular Research
    • Interventional Cardiology

    Background:

    • Myocardial infarction (MI) is characterized by oxygen deprivation in the heart muscle.
    • Early reperfusion is a key strategy for limiting infarct size and preserving cardiac function.

    Purpose of the Study:

    • To evaluate the efficacy of early reperfusion therapy in reducing infarct size and improving functional outcomes.
    • To identify factors influencing the success of thrombolytic therapy and patient prognosis.

    Main Methods:

    • Assessment of global ejection fraction via angiography and gated blood pool imaging.
    • Radioisotope perfusion imaging to quantify infarct size reduction.
    • Analysis of patient outcomes based on thrombolysis success, creatine kinase levels, and collateral vessel presence.

    Main Results:

    • Thrombolytic therapy demonstrated efficacy through improved ejection fraction and reduced perfusion defects.
    • Shorter ischemic periods and greater collateral circulation correlated with less ischemic damage in successful thrombolysis cases.
    • Combination therapy (intravenous and intracoronary streptokinase) shortened ischemic times compared to monotherapy.

    Conclusions:

    • Early reperfusion, particularly within 3-5 hours, is recommended to minimize myocardial damage.
    • Immediate revascularization after reperfusion can reduce mortality in patients with reocclusion or severe stenosis.
    • Successful reperfusion offers significant benefits for specific patient subgroups, including those with prior MI or extensive perfusion defects.

    Related Experiment Videos