Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is Genetic Engineering?00:49

What is Genetic Engineering?

80.4K
Overview
80.4K
Seedless Vascular Plants03:24

Seedless Vascular Plants

67.7K
Seedless Vascular Plants Were the First Tall Plants on Earth
67.7K
Plant Tissue Culture02:57

Plant Tissue Culture

40.8K
Plant tissue culture is widely used in both primary and applied science. Applications range from plant development studies to functional gene studies, crop improvement, commercial micropropagation, virus elimination, and conservation of rare species.
40.8K
Vascular Spasm01:16

Vascular Spasm

3.8K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
3.8K
Overview of the Vascular System01:20

Overview of the Vascular System

3.6K
The vascular system comprises an extensive network of arteries, capillaries, and veins. The vascular system can be broadly divided into the blood and lymphatic systems. Typically, blood vessels can be categorized into three histological regions: tunica intima, tunica media, and tunica adventitia. The tunica intima consists of a single layer of endothelial cells attached to the basal lamina. Underlying the basal lamina is a connective tissue layer and an elastic lamina that gives stability and...
3.6K
Vascular Resistance01:20

Vascular Resistance

11.2K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
11.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Using the Consolidated Framework for Implementation Research (CFIR) to explore mutual-help group implementation challenges in college recovery programs.

BMC health services research·2026
Same author

Assessing movement quality in individuals with Duchenne muscular dystrophy utilizing accelerometry: Comparisons with healthy controls.

PLOS digital health·2026
Same author

Return to Sport and Exercise After Direct Anterior Approach Total Hip Arthroplasty: Minimum Five-Year Outcomes.

The Journal of arthroplasty·2026
Same author

Strategies for Aortic Root Measurement in Patients Undergoing Surveillance for Thoracic Aortic Disease.

Journal of clinical medicine·2026
Same author

Longitudinal changes in cardiac function, volumes and fibrosis in a prospective cohort of female Duchenne and Becker muscular dystrophy carriers.

International journal of cardiology·2026
Same author

Femoral component collar and calcar contact during total hip arthroplasty: gap incidence, subsidence, and biomechanical testing - a scoping review.

Orthopedic reviews·2026

Related Experiment Video

Updated: Feb 12, 2026

Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
11:17

Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring

Published on: April 3, 2015

12.3K

Toward a patient-specific tissue engineered vascular graft.

Cameron Best1,2, Robert Strouse3, Kan Hor4

  • 1Center for Regenerative Medicine, The Research Institute, Nationwide Children's Hospital, Columbus, OH, USA.

Journal of Tissue Engineering
|March 24, 2018
PubMed
Summary

Three-dimensional printing enables patient-specific vascular grafts for congenital heart disease. This technology offers a custom solution for complex cases, advancing tissue engineering for pediatric cardiac surgery.

Keywords:
3D-printingFontan operationTissue-engineered vascular graftcell seedingpatient-specific modeling

More Related Videos

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
09:55

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber

Published on: May 30, 2016

9.4K
Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor
11:22

Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor

Published on: June 14, 2011

17.8K

Related Experiment Videos

Last Updated: Feb 12, 2026

Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring
11:17

Surgical Technique for the Implantation of Tissue Engineered Vascular Grafts and Subsequent In Vivo Monitoring

Published on: April 3, 2015

12.3K
Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber
09:55

Tissue Engineering by Intrinsic Vascularization in an In Vivo Tissue Engineering Chamber

Published on: May 30, 2016

9.4K
Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor
11:22

Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor

Published on: June 14, 2011

17.8K

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Pediatric Cardiology

Background:

  • Congenital heart disease in newborns often requires complex vascular repairs.
  • Current tissue-engineered vascular grafts may not meet intricate anatomical demands.
  • Patient-specific solutions are needed to improve surgical outcomes.

Purpose of the Study:

  • To explore the feasibility of using three-dimensional (3D) printing for patient-specific tissue-engineered vascular grafts.
  • To adapt 3D printing technology for creating custom grafts and seeding devices for complex pediatric cardiac cases.
  • To demonstrate a proof of concept for rationally designed, patient-specific vascular grafts.

Main Methods:

  • 3D printing of a closed-disposable seeding device for tissue-engineered vascular grafts.
  • Validation of the 3D-printed seeding device against traditional methods using ovine bone marrow-derived mononuclear cells.
  • Design and 3D printing of a patient-specific seeding apparatus based on preoperative imaging.

Main Results:

  • The 3D-printed seeding device demonstrated equivalent performance to the open seeding technique.
  • A custom seeding apparatus was successfully designed and fabricated using a fused deposition modeler.
  • This study represents a significant step towards patient-specific tissue-engineered vascular grafts.

Conclusions:

  • Three-dimensional printing technology can be adapted to create patient-specific tissue-engineered vascular grafts and associated devices.
  • This approach holds promise for addressing complex anatomical challenges in treating newborns with congenital heart disease.
  • Further development is warranted to advance this technology towards clinical application.