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Updated: Feb 12, 2026
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In Vivo Multimodal Imaging and Analysis of Mouse Laser-Induced Choroidal Neovascularization Model
Published on: January 21, 2018
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Optical coherence tomography angiography and choroidal neovascularization in multifocal choroiditis: A descriptive
Cyril Dutheil1, Jean-François Korobelnik1,2, Marie-Noëlle Delyfer1,2
11 Department of Ophthalmology, Bordeaux University Hospital, Amélie Raba-Léon, Bordeaux, France.
European Journal of Ophthalmology
|March 24, 2018
Summary
Optical coherence tomography angiography effectively identifies choroidal neovascularization in multifocal choroiditis. However, it struggles to distinguish between active and inactive choroidal neovascularization lesions.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Multifocal choroiditis is an inflammatory eye condition.
- Choroidal neovascularization (CNV) can complicate multifocal choroiditis, potentially leading to vision loss.
Purpose of the Study:
- To evaluate optical coherence tomography angiography (OCTA) for identifying CNV in multifocal choroiditis.
- To characterize the OCTA features of active and inactive CNV in this patient group.
Main Methods:
- Retrospective analysis of 10 eyes with multifocal choroiditis and CNV.
- OCTA imaging (AngioPlex™ CIRRUS™ HD-OCT) was used for morphological assessment of CNV.
Main Results:
- OCTA successfully detected all instances of CNV.
- Active CNV showed well-circumscribed margins (67%) and interlacing shapes (83%).
- Inactive CNV presented with poorly circumscribed margins (75%) and a 'dead tree' appearance (50%).
Conclusions:
- OCTA is valuable for diagnosing CNV in multifocal choroiditis.
- Distinguishing active from inactive CNV using OCTA remains challenging.
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