Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

422
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
422
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

1.2K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.2K
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

519
Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
519
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

302
Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
302
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

448
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
448
Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

734
Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
734

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reversible podocytopathy in a patient with blastoid-variant mantle cell lymphoma: A case of paraneoplastic FSGS and a literature review.

Nefrologia·2026
Same author

Development and validation of an instrument to assess public perception of cancer primary prevention information.

Archives of public health = Archives belges de sante publique·2026
Same author

Development and Preliminary Psychometric Evaluation of the ACRIS-CS: A Theory-Based Measure of Prospective Acceptability of Cognitive Rehabilitation in Cancer Survivors.

Journal of clinical medicine·2026
Same author

Implementing systematic early protocol biopsies in routine practice: An exploratory real-world study.

Nephrologie & therapeutique·2026
Same author

Myxoma of the Pulmonary Valve: A Case Report and Review of the Literature.

Cureus·2026
Same author

Factors Contributing to Screen Exposure in Preschool Children and Its Associated Outcomes: A Systematic Review.

Child: care, health and development·2026
Same journal

Cardiac rehabilitation programs for heart failure patients in the time of COVID-19.

Revista portuguesa de cardiologia·2024
Same journal

COVID-19 and cardiovascular comorbidities: An update.

Revista portuguesa de cardiologia·2024
Same journal

Endomyocardial biopsy. Do it whenever you need it!

Revista portuguesa de cardiologia·2024
Same journal

Caring for cardiac patients amidst the SARS-CoV-2 pandemic: The scrambled pieces of the puzzle.

Revista portuguesa de cardiologia·2024
Same journal

ST-elevation acute coronary syndrome without obstructive coronary disease in a COVID-19 patient.

Revista portuguesa de cardiologia·2024
Same journal

Giant right coronary artery aneurysm and fistula into the coronary sinus.

Revista portuguesa de cardiologia·2021
See all related articles

Related Experiment Video

Updated: Feb 12, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.3K

Coronary artery abnormalities: Current clinical issues.

Helena Sousa1, Jorge Casanova2

  • 1Faculdade de Medicina da Universidade do Porto, Porto, Portugal.

Revista Portuguesa De Cardiologia
|March 25, 2018
PubMed
Summary
This summary is machine-generated.

Surgery for anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS) is low-risk. While indications are clear for symptomatic patients, a more assertive surgical approach is suggested for asymptomatic individuals with anomalous right coronary arteries, especially if young or active.

Keywords:
Anomalous aortic origin of the coronary arteryCardiac surgeryCirurgia cardíacaInterarterial courseOrigem aórtica anómala da artéria coronáriaSeio de ValsalvaSinus of ValsalvaTrajeto interarterial

More Related Videos

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice
08:30

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Published on: April 19, 2011

22.1K
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

16.1K

Related Experiment Videos

Last Updated: Feb 12, 2026

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA
13:10

Direct Re-implantation of Left Coronary Artery into the Aorta in Adults with Anomalous Origin of Left Coronary Artery from the Pulmonary Artery ALCAPA

Published on: April 24, 2017

19.3K
Use of a Hanging Weight System for Coronary Artery Occlusion in Mice
08:30

Use of a Hanging Weight System for Coronary Artery Occlusion in Mice

Published on: April 19, 2011

22.1K
Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans
04:40

Identifying Coronary Artery Calcification on Non-gated Computed Tomography Scans

Published on: August 28, 2018

16.1K

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Congenital Heart Disease

Background:

  • Anomalous coronary arteries arising from the opposite sinus of Valsalva (ACAOS) present a spectrum of clinical manifestations, from asymptomatic cases to sudden cardiac death.
  • Existing guidelines for surgical intervention in ACAOS are debated, particularly for certain patient subgroups.

Purpose of the Study:

  • To evaluate the outcomes of surgical intervention for ACAOS.
  • To review current literature on ACAOS, focusing on clinical presentation, surgical indications, and results.
  • To propose refined indications for surgery in specific ACAOS patient populations.

Main Methods:

  • Retrospective review of adult patients diagnosed with ACAOS between 2007 and 2016.
  • Collection and summarization of demographic, clinical, perioperative, and follow-up data.
  • Comprehensive literature review on ACAOS clinical presentation, surgical indications, and outcomes.

Main Results:

  • Seven symptomatic ACAOS patients underwent surgery with successful recovery and no recurrence of myocardial ischemia.
  • One asymptomatic patient with anomalous right coronary artery (RCA) was managed medically without ischemic events.
  • A case of sudden cardiac death in an untreated anomalous left coronary artery (LCA) patient highlights potential risks.

Conclusions:

  • Surgical treatment for ACAOS is associated with low risk and high operative survival rates.
  • Surgical indications are well-established for interarterial anomalous LCA and symptomatic interarterial anomalous RCA.
  • An assertive surgical approach is recommended for asymptomatic patients with interarterial anomalous RCA, particularly if young or physically active.