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A Modular System for the Design of Stimuli-Responsive Multifunctional Nanoparticle Aggregates by Use of Host-Guest
Sabrina Engel1, Nadja Möller1, Lucas Stricker1
1Organic Chemistry Institute and Center for Soft Nanoscience, Westfälische Wilhelms-Universität Münster, Corrensstrasse 40, 48149, Münster, Germany.
Abstract:
A self-assembly approach for the design of multifunctional nanomaterials consisting of different nanoparticles (gold, iron oxide, and lanthanide-doped LiYF4 ) is developed. This modular system takes advantage of the light-responsive supramolecular host-guest chemistry of β-cyclodextrin and arylazopyrazole, which enables the dynamic and reversible self-assembly of particles to spherical nanoparticle aggregates in aqueous solution. Due to the magnetic iron oxide nanoparticles, the aggregates can be manipulated by an external magnetic field leading to the formation of linear structures. As a result of the integration of upconversion nanoparticles, the aggregates are additionally responsive to near-infrared light and can be redispersed by use of the upconversion effect. By varying the nanoparticle and linker concentrations the composition, size, shape, and properties of the multifunctional nanoparticle aggregates can be fine-tuned.
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