Related Experiment Video
Updated: Feb 12, 2026

Enema of Traditional Chinese Medicine for Patients with Severe Acute Pancreatitis
Published on: January 27, 2023
Screening of bioactive components from traditional Chinese medicines using cell membrane chromatography coupled with
Shengli Han1,2, Yanni Lv1, Fen Wei1
1School of Pharmacy, Xi'an Jiaotong University, Xi'an, Shaanxi, P. R. China.
Introduction:
Cell membrane chromatography (CMC), as a highly selective type of affinity chromatography, has been demonstrated as an effective method to screen bioactive components acting on specific receptor from a complicated biological system.
Objective:
To review the recent research progress and the technical applications of these analytical methods using CMC combined with gas chromatography-mass spectrometry, (GC/MS) and liquid chromatography-mass spectrometry (LC/MS).
Methodology:
In this review, we briefly introduce the CMC offline GC/MS, CMC online GC/MS, CMC offline LC/MS, and CMC online LC/MS system. And the practical application of these technologies is also enumerated. Then the future of these technologies and research methods were discussed.
Results:
Many bioactive components interacting with specific receptors have been screened and identified in traditional Chinese medicines.
Conclusion:
CMC technique has been combined with GC/MS and HPLC/MS and these combined systems have been successfully used to screen bioactive components acting on specific receptors from a complicated biological system.
Related Concept Videos
Gas Chromatography–Mass Spectrometry (GC–MS)
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
Inductively Coupled Plasma-Mass Spectrometry (ICP-MS): Interferences
Inductively Coupled Plasma–Mass Spectrometry (ICP–MS): Overview
Mass Spectrometry: Overview
Tandem Mass Spectrometry
Mass Spectrometry of Amines

