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The Use of Multivitamin/Multimineral Supplements: A Modified Delphi Consensus Panel Report
Jeffrey B Blumberg1, Hellas Cena2, Susan I Barr3
1Friedman School of Nutrition Science and Policy, Tufts University, Boston, Massachusetts.
Multivitamin/multimineral supplements (MVMS) can improve micronutrient intake and support health, especially for those with deficiencies. Long-term use is safe for healthy adults, but evidence for chronic disease prevention is insufficient.
Area of Science:
- Nutritional Science
- Public Health
- Dietary Supplements
Background:
- Mixed evidence on dietary supplements, particularly multivitamin/multimineral supplements (MVMS), complicates professional recommendations.
- Expert consensus is needed to clarify the role of MVMS in supporting human health.
Purpose of the Study:
- To develop consensus statements on the use of MVMS for optimal human health.
- To provide evidence-based guidance for healthcare professionals and the public.
Main Methods:
- A panel of 14 international experts in nutritional science and health care was convened.
- A modified Delphi process, including remote voting and a roundtable discussion, was employed.
- Consensus was defined as ≥80% agreement on statements rated on a 5-point Likert scale.
Main Results:
- Consensus was reached on all statements.
- MVMS can improve micronutrient intake, especially when targeting population-specific deficiencies.
- MVMS are safe for long-term use in healthy adults within recommended limits.
- Evidence for primary prevention of chronic diseases (e.g., cardiovascular disease, cancer) by MVMS is insufficient.
- MVMS can benefit specific subpopulations (e.g., pregnant women, older adults) and individuals with existing medical conditions experiencing micronutrient inadequacies.
Conclusions:
- MVMS can be a valuable tool to ensure adequate micronutrient intake and support biological functions necessary for health.
- Individualized MVMS formulations may be beneficial.
- Addressing micronutrient inadequacies through MVMS can provide health benefits for at-risk populations.
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