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Related Concept Videos

Somatic Spinal Reflexes01:22

Somatic Spinal Reflexes

Somatic spinal reflexes are rapid, involuntary muscular responses to external stimuli that involve the somatic musculature and the spinal cord.
One of the most well-known somatic spinal reflexes is the stretch reflex, which is activated by the sudden stretching of a muscle. This reflex involves the activation of specialized sensory receptors called muscle spindles, which are located in the muscle tissue and detect changes in the length and speed of muscle contractions. When a muscle is suddenly...

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Related Experiment Video

Updated: Jul 14, 2026

Methods to Quantify Pharmacologically Induced Alterations in Motor Function in Human Incomplete SCI
14:55

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Published on: April 18, 2011

Sacral Neuromodulation and Twiddler's Syndrome.

Ted M Roth1

  • 1Central Maine Urogynecology, Central Maine Medical Center, Lewiston, ME.

Urology
|March 26, 2018
PubMed
Summary

Twiddler's syndrome, a known issue with implanted devices, can occur with sacral neuromodulation. This case highlights the risk of generator manipulation leading to lead complications.

Area of Science:

  • Neurology
  • Biomedical Engineering
  • Implantable Devices

Background:

  • Twiddler's syndrome involves manipulation of implantable generators, causing lead issues.
  • It's recognized in pacemakers, defibrillators, deep brain stimulators, and drug delivery systems.

Observation:

  • This report details a case of Twiddler's syndrome following sacral neuromodulation therapy.
  • The patient's actions led to generator malposition within the subcutaneous pocket.

Findings:

  • The manipulation resulted in complications associated with the implanted lead.
  • This demonstrates a novel presentation of Twiddler's syndrome in sacral neuromodulation.

Implications:

  • Highlights the need for patient education regarding implantable device handling.

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  • Suggests vigilance for Twiddler's syndrome in sacral neuromodulation patients.
  • Informs future device design and patient management protocols.