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Related Experiment Video

Updated: Feb 12, 2026

Assessment of the Metabolic Profile of Primary Leukemia Cells

Published on: November 21, 2018

Residential mobility and childhood leukemia.

A T Amoon¹, S Oksuzyan², C M Crespi³

¹Department of Epidemiology, University of California Los Angeles Fielding School of Public Health, 650 Charles E. Young Drive South, Los Angeles, CA 90095-1772, USA.

Environmental Research

|March 26, 2018

Summary

Residential mobility in childhood leukemia studies is often overlooked. This study found mobility is not a likely cause for the observed associations between power lines and childhood leukemia.

Keywords:

Childhood leukemia Electro-magnetic fields Power lines Residential mobility

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Area of Science:

Environmental Epidemiology
Pediatric Oncology
Public Health

Background:

Childhood leukemia studies often do not account for residential mobility.
Residential mobility can introduce bias (selection, confounding, measurement error) into environmental exposure studies.
The California Powerline Study (CAPS) data was used to investigate the role of mobility.

Purpose of the Study:

To assess the impact of residential mobility on childhood leukemia risk estimates.
To determine if residential mobility confounds the association between power line proximity and childhood leukemia.
To disentangle the effects of residential mobility in environmental exposure research.

Main Methods:

Population-based case-control study of childhood leukemia in California (1988-2008).
Used stratified logistic regression, case-only analysis, and propensity-score adjustments to model mobility predictors.
Analyzed association between residential mobility, sociodemographic factors, and proximity to high-voltage power lines.

Main Results:

Children who moved were more likely to be older, live in non-single-family homes, have younger mothers, fewer siblings, and lower socioeconomic status.
Adjusting for mobility-related factors, particularly dwelling type, increased the odds ratios for leukemia associated with proximity to 200+ kilovolt lines and calculated magnetic fields.
The association between power line exposure and childhood leukemia was not explained by residential mobility.

Conclusions:

Childhood leukemia cases exhibited varied residential mobility based on sociodemographic factors.
Residential mobility did not correlate with proximity to power lines or magnetic field exposure levels.
Residential mobility is unlikely to explain the observed associations between power line exposure and childhood leukemia.