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Updated: Feb 12, 2026
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Methods to Study Changes in Inherent Protein Aggregation with Age in Caenorhabditis elegans
Published on: November 26, 2017
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Atmospheric skin aging-Contributors and inhibitors
David McDaniel1,2,3,4, Patricia Farris5,6, Giuseppe Valacchi7,8
1McDaniel Laser and Cosmetic Center and McDaniel Institute of Anti-Aging Research, Virginia Beach, VA, USA.
Journal of Cosmetic Dermatology
|March 26, 2018
Summary
Environmental factors like sunlight and pollution accelerate skin aging by generating reactive oxygen species (ROS). Understanding these aggressors is key to developing new treatments and preventing premature skin aging.
Area of Science:
- Dermatology
- Environmental Science
- Biochemistry
Background:
- Cutaneous aging comprises intrinsic (genetic) and extrinsic (environmental) factors.
- Sunlight (UVA, UVB), visible light, infrared radiation, and air pollution contribute to premature skin aging.
- Environmental damage results from reactive oxygen species (ROS) causing oxidative stress.
Purpose of the Study:
- To review atmospheric factors contributing to skin aging.
- To discuss the mechanisms of skin damage.
- To explore novel therapeutic strategies for prevention and treatment.
Main Methods:
- Literature review of environmental aggressors and their effects on skin.
- Analysis of the role of reactive oxygen species (ROS) in skin damage.
- Discussion of current and emerging therapeutic interventions.
Main Results:
- UVA, UVB, visible light, infrared radiation, and air pollution are significant extrinsic aging factors.
- ROS generation is a central mechanism in environmentally induced skin damage.
- Antioxidants and novel topical treatments show promise in mitigating skin aging.
Conclusions:
- Atmospheric factors significantly impact skin aging through oxidative stress.
- Preventative measures like sunscreens and topical antioxidants are crucial.
- Further research into novel therapeutic modalities is needed to combat premature skin aging.
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