NEW APPROACHES IN THE DIAGNOSTIC OF ICHTHYOSIS DISORDERS

The aim of this study was to study the macroscopic changes in the skin of patients with various forms of ichthyosis to improve and optimize treatment. A comprehensive examination of 12 patients with ichthyosis under the supervision of a dermatovenereologist was conducted at VOKSHVD. For the diagnosis of macroscopic skin changes, the dermatoscopy was performed by the HEINE DELTA 20 ® (Germany) apparatus, the results were recorded with a Canon 550D camera (Japan) at 1:35 or 1:30, with a sensitivity of IZO 200 using an adapter included with the dermatoscope. All affected skin were examined, which were compared with unharmed ones. The task was performed using the algorithm developed by us for dermatoscopic assessment of the severity of ichthyosis. The presence of typical dermatoscopic signs in examined patients with ichthyosis, which is manifested by the smoothness of the skin pattern, the presence of a pseudo-pigmental mesh, formed by keratin of scales in the form of lines, mesh and loop structures resembling cerebriform components, are established. The algorithm of estimation of expressiveness of dermatoscopic features for patients with light and severe clinical course of ichthyosis is proposed. Also, specific dermatological signs were observed in the mild clinical course of ichthyosis, in particular the phenomenon of «sparkling champagne», and in severe clinical course, the «melting ice» phenomal. The use of the dermatoscopic method makes it possible to objectively evaluate the severity of the ichthyosis and apply a differentiated approach to choosing the most effective treatment schemes.