Related Experiment Video
Updated: Feb 12, 2026

Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Enantioselective complexation of 1-phenylethanol with chiral compounds bearing urea moiety
Petra Cuřínová1, Martin Dračínský2, Martin Jakubec1
1Institute of Chemical Process Fundamentals of the Czech Academy of Sciences, Prague, Czech Republic.
Abstract:
A detailed study of diastereomeric complexes of chiral ureido-1,1'-binaphthalene derivatives with chiral 1-phenylethanol showed that a derivative bearing only one urea unit makes five times more stable complex with (S)-enantiomer than with (R)-enantiomer of the alcohol. This phenomenon could be used in chiral discrimination processes. The influence of individual parts of the structure on the complexation properties is shown. The probable structure of diastereomeric complexes based on experimental results and computational methods is proposed.
Related Concept Videos
Chirality
Chiral objects exhibit a sense of handedness when they interact with another chiral object. For example, our left foot can only fit in the left shoe and not in the right shoe. Achiral objects — objects that have...
Urea Cycle
Chirality in Nature
Coordination Compounds and Nomenclature
Azimuths and Bearings
Collar Bearings

