Operator volume is not associated with mortality following percutaneous coronary intervention: insights from the

William Hulme1, Matthew Sperrin1, Nick Curzen2

  • 1Farr Institute, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.

European Heart Journal
|March 27, 2018
PubMed

Insights

Operator volume did not significantly impact 30-day mortality for percutaneous coronary intervention (PCI) in England and Wales. This study found no evidence of a volume-outcome relationship in contemporary UK practice, suggesting current PCI outcomes are not volume-dependent.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Health Services Research

Background:

  • The relationship between operator volume and outcomes for percutaneous coronary intervention (PCI) is debated.
  • Previous studies may not reflect current practices in the radial, acute coronary syndrome-dominant era.
  • Contemporary data on volume-outcome relationships in PCI are limited.

Purpose of the Study:

  • To assess the association between operator volume and 30-day mortality in a contemporary PCI cohort in England and Wales.
  • To re-evaluate the relevance of historical volume-outcome relationships in modern interventional cardiology.
  • To determine if operator experience influences patient outcomes after PCI.

Main Methods:

  • Observational cohort study using the British Cardiovascular Intervention Society PCI database (2013-2014).
  • Analysis of 133,970 PCI procedures, with operator volume defined as procedures in the preceding 12 months.
  • Mixed effects multiple logistic regression used to adjust for confounders and account for operator/center effects.

Main Results:

  • The overall 30-day mortality rate was 2.6%.
  • After adjusting for case-mix, operator volume showed a negligible association with 30-day mortality (OR per 100 procedures = 0.99, P=0.725).
  • Sensitivity analyses confirmed these findings in high-risk PCI subsets and for in-hospital outcomes.

Conclusions:

  • No evidence suggests that 30-day mortality in the UK differs based on operator volume for PCI.
  • Volume-outcome relationships in PCI warrant continued monitoring due to potential future practice changes.
  • Contemporary PCI practice in the UK does not demonstrate a significant link between operator volume and patient mortality.
Abstract

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