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Updated: Feb 12, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Operator volume is not associated with mortality following percutaneous coronary intervention: insights from the
William Hulme1, Matthew Sperrin1, Nick Curzen2
1Farr Institute, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK.
Insights
Operator volume did not significantly impact 30-day mortality for percutaneous coronary intervention (PCI) in England and Wales. This study found no evidence of a volume-outcome relationship in contemporary UK practice, suggesting current PCI outcomes are not volume-dependent.
Area of Science:
- Cardiology
- Interventional Cardiology
- Health Services Research
Background:
- The relationship between operator volume and outcomes for percutaneous coronary intervention (PCI) is debated.
- Previous studies may not reflect current practices in the radial, acute coronary syndrome-dominant era.
- Contemporary data on volume-outcome relationships in PCI are limited.
Purpose of the Study:
- To assess the association between operator volume and 30-day mortality in a contemporary PCI cohort in England and Wales.
- To re-evaluate the relevance of historical volume-outcome relationships in modern interventional cardiology.
- To determine if operator experience influences patient outcomes after PCI.
Main Methods:
- Observational cohort study using the British Cardiovascular Intervention Society PCI database (2013-2014).
- Analysis of 133,970 PCI procedures, with operator volume defined as procedures in the preceding 12 months.
- Mixed effects multiple logistic regression used to adjust for confounders and account for operator/center effects.
Main Results:
- The overall 30-day mortality rate was 2.6%.
- After adjusting for case-mix, operator volume showed a negligible association with 30-day mortality (OR per 100 procedures = 0.99, P=0.725).
- Sensitivity analyses confirmed these findings in high-risk PCI subsets and for in-hospital outcomes.
Conclusions:
- No evidence suggests that 30-day mortality in the UK differs based on operator volume for PCI.
- Volume-outcome relationships in PCI warrant continued monitoring due to potential future practice changes.
- Contemporary PCI practice in the UK does not demonstrate a significant link between operator volume and patient mortality.
Aims:
The relationship between operator volume and outcomes for percutaneous coronary intervention (PCI) has been studied in the past, but recent analyses of national data covering the modern radial, acute coronary syndrome-dominant era are limited. Changing in case-mix, practice, and service provision mean that previously described volume-outcome relationships may no longer be relevant, and a reassessment in contemporary practice is needed. We aim to assess whether operator volume is associated with independently reported 30-day mortality in a contemporary PCI cohort.
Methods And Results:
This observational cohort study analysed procedures recorded in the British Cardiovascular Intervention Society PCI database from 2013 to 2014 in England and Wales. Mixed effects multiple logistic regression modelling was used to account for operator and centre level effects and to adjust for potential confounders. Volume is defined as the total number of procedures the operator was responsible for in the previous 12 months. A total of 133 970 procedures were analysed. Median volume across all procedures was 178 per year (interquartile range 128-239). The 30-day mortality rate was 2.6%. After adjustment for case-mix, the association between volume and mortality was negligible (odds ratio per 100 procedures 0.99, 95% confidence interval 0.93-1.05; P = 0.725). Sensitivity analyses showed similar results amongst high-risk PCI subsets and in-hospital outcomes.
Conclusion:
There is no evidence that mortality differs by operator volume in the UK. Volume-outcome relationships in PCI should be carefully monitored in response to future changes in practice.
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