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Updated: Feb 12, 2026

Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
Defining Success in Lung Transplantation: From Survival to Quality of Life
Nicholas A Kolaitis1, Jonathan P Singer1
1Department of Medicine, School of Medicine, University of California, San Francisco, San Francisco, California.
Abstract:
Lung transplantation (LT) has the potential to extend survival and improve quality of life (QOL) for patients suffering from end-stage lung disease. This review describes the many ways in which success can be defined in LT. It evaluates the improvements in survival outcomes after LT over time, and describes ways to measure the success of LT other than survival after transplantation. It also addresses the importance of patient-centered outcomes and how improvements in health-related quality of life (HRQL) are pivotal to defining success within LT.
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