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Updated: Feb 12, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Knowledge of the Brain Death Concept Among the Population of Havana, Cuba
A Ríos1, A I López-Navas2, Á Sánchez3
1Proyecto Colaborativo Internacional Donante ("International Collaborative Donor Project"), Murcia, Spain; Department of Surgery, Paediatrics, Obstetrics and Gynaecology, University of Murcia, Murcia, Spain; Transplant Unit, Surgery Service, IMIB-Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain.
Background:
One of the main reasons against organ donation is the fear of apparent death due to ignorance of the brain death concept. Our aim was to assess knowledge about and acceptance of the brain death concept among the population of Havana, Cuba.
Methods:
The population screened, stratified by gender and age, included those >15 years old and living in Havana, Cuba. The appraisal tool utilized was a questionnaire on attitude toward organ donation ("PCID-DTO Ríos"). A random selection of individuals were surveyed according to the stratification. Cuba's census data were used. The participation was anonymized and self-administered. The verbal consent of participants was provided.
Results:
There were 920 respondents: 31% (n = 282) knew the concept of brain death and accepted it; 57% (n = 529) did not; and 12% (n = 109) had a misperception, or did not accept brain death as a person's death. Those who knew and accepted the concept had a more favorable attitude toward their own organ donation after death (85% vs 61%; P < .001). The psychosocial factors related to the knowledge of brain death concept were: the gender (P = .002), to make up for speaking at a family level about the organ transplant (P < .001), the couple's opinion about the organ donation (P < .001) and the religion (P < .001).
Conclusion:
The brain death concept is not well understood in the population of Havana, Cuba.
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