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Updated: Feb 12, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
Post-treatment surveillance imaging in lymphoma
Susan M Hiniker1, Richard T Hoppe1
1Department of Radiation Oncology, Stanford University, Stanford, CA.
Post-treatment surveillance imaging in lymphoma is controversial. Current data suggest limited clinical benefit for asymptomatic patients, though research continues to identify high-risk groups who may benefit.
Area of Science:
- Oncology
- Radiology
- Hematology
Background:
- Post-treatment management of lymphoma patients often includes surveillance imaging.
- The primary goal of surveillance imaging is early detection of relapse for improved salvage therapy and cure potential.
- Current evidence supporting routine surveillance imaging in asymptomatic lymphoma patients is limited.
Purpose of the Study:
- To review and summarize existing data on post-treatment surveillance imaging in lymphoma.
- To evaluate the clinical benefit of surveillance imaging in asymptomatic lymphoma patients.
- To discuss ongoing efforts in identifying patient subsets who might benefit from surveillance imaging.
Main Methods:
- Literature review and synthesis of current data on lymphoma surveillance imaging.
- Analysis of studies evaluating the efficacy and clinical utility of post-treatment imaging.
- Consideration of the costs and benefits associated with surveillance imaging practices.
Main Results:
- The majority of studies indicate no significant clinical benefit from surveillance imaging in asymptomatic lymphoma patients.
- Limited data exist to support the routine use of surveillance imaging after treatment completion.
- Research is ongoing to identify specific patient subgroups at higher risk of relapse who may benefit from imaging.
Conclusions:
- Routine post-treatment surveillance imaging in asymptomatic lymphoma patients is not well-supported by current evidence.
- The clinical utility and cost-effectiveness of surveillance imaging require careful consideration.
- Further research is needed to define the role of surveillance imaging in select lymphoma patient populations.
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