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Related Experiment Videos

Functional blockage of open comedones.

N B Simpson1

  • 1Dermatology Department, Royal Infirmary, Glasgow, U.K.

The British Journal of Dermatology
|July 1, 1987
PubMed
Summary
This summary is machine-generated.

Sebum excretion rates correlate between different body areas and sides. Contrary to assumptions, blackheads show reduced sebum flow, suggesting obstruction, not free flow, in acne development.

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Area of Science:

  • Dermatology
  • Cutaneous Biology
  • Sebaceous Gland Physiology

Background:

  • Sebaceous glands produce sebum, crucial for skin health.
  • Understanding sebum excretion dynamics is vital for acne research.
  • Open comedones (blackheads) are a key acne feature.

Purpose of the Study:

  • To quantify sebum excretion rates (SER) across different skin sites.
  • To investigate the relationship between SER on the back and forehead.
  • To determine if open comedones impede sebum outflow.

Main Methods:

  • Photometric technique used for measuring sebum excretion rate.
  • SER measurements taken on the upper back (left and right) and forehead.
  • SER compared between normal skin and skin overlying open comedones.

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Main Results:

  • High correlation found in SER between left and right upper back.
  • Significant correlation observed between back and forehead SER.
  • SER overlying open comedones was significantly lower than normal skin.

Conclusions:

  • Sebum excretion is consistent across different body areas.
  • Open comedones represent a functional obstruction to sebum outflow.
  • The lack of inflammation in open comedones is not due to free sebum flow.