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Dermatitis in a rubber tyre factory.

A M Zina1, P G Bedello, D Cane

  • 1Clinica Dermatologica, Torino, Italy.

Contact Dermatitis
|July 1, 1987
PubMed
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An occupational dermatitis outbreak in a rubber factory was investigated. Sensitization to 2-(2'-4'dinitrophenylthio)benzothiazole, a rubber chemical, was identified as the cause.

Area of Science:

  • Occupational Health
  • Dermatology
  • Chemical Toxicology

Background:

  • Occupational dermatitis is a common issue in industrial settings.
  • Rubber manufacturing involves exposure to various chemicals that can cause skin sensitization.

Purpose of the Study:

  • To investigate an unusual outbreak of occupational dermatitis in a rubber tyre factory.
  • To identify the specific causative agent responsible for the observed sensitization.

Main Methods:

  • Clinical observation of dermatitis cases.
  • Patch testing with specific chemicals, including MBT derivative, MBT mix, and dinitrophenol.
  • Identification of the sensitizing contaminant through further investigation.

Main Results:

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  • A high rate of sensitization was observed in factory workers.
  • The sensitization was specifically linked to 2-(2 ' 4 ' dinitrophenylthio)benzothiazole, an MBT derivative.
  • Negative patch tests for MBT mix and dinitrophenol suggested a contaminant was responsible.

Conclusions:

  • The outbreak of occupational dermatitis was caused by sensitization to a contaminant.
  • 2,4-Dinitrophenylthio)benzothiazole (DNCB) was identified as the specific substance responsible for the high sensitization rate.