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Published on: February 15, 2008
Strabismus surgery for diplopia in chronic progressive external ophthalmoplegia
Klio I Chatzistefanou1, Dimitrios Brouzas2, Ioannis Asproudis3
1Strabismus Service, First Department of Ophthalmology, National and Kapodistrian University of Athens School of Medicine, 32 Socratous Street, Voula, 16673, Athens, Greece. kliochat@med.uoa.gr.
Background:
To report midterm outcomes of strabismus strategy for management of diplopia in chronic progressive external ophthalmoplegia and specific surgical planning rationale.
Design:
Retrospective interventional case series.
Results:
Two patients, a 26-year-old male and a 36-year-old female, diagnosed with chronic progressive external ophthalmoplegia presented with blepharoptosis and intermittent diplopia. Ocular motility examination was significant for bilateral profound impairment of adduction with relative preservation of abduction, infraduction and elevation. Control of intermittent exotropia gradually worsened over 3 and 1.5 years of follow-up, respectively, in the presence of documented stability of the angle of exodeviation. Strabismus surgery involving modest amounts of bilateral medial rectus resection and lateral rectus recessions was undertaken. Surgical intervention was successful in controlling alignment in primary position and alleviating diplopia and asthenopia after 9 and 8 years of follow-up time, respectively, despite slow progression of ophthalmoplegia.
Conclusion:
Bilateral selective impairment of adduction and intermittent exotropia may be the presenting ocular motility disturbance in chronic progressive external ophthalmoplegia. Properly designed strabismus surgery may provide sustainable, in the midterm, control of alignment and symptomatic relief in selected patients with CPEO.
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