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In Vitro Scratch Assay to Demonstrate Effects of Arsenic on Skin Cell Migration
Published on: February 23, 2019
Association between skin lesion and arsenic concentration in hair by mixed bivariate model in chronic arsenic
Arabinda Das1, Anirban Biswas2, Debendra Nath Guha Mazumder3
1Department of Statistics, Acharya Prafulla Chandra College, Kolkata, West Bengal, 700131, India. ara.das@gmail.com.
Abstract:
Skin lesion is one of the important health hazards caused by high intake of arsenic through drinking water and diet, and the other hazards include several types of cancers (viz. skin, lung and urinary bladder), ischemic heart disease, hypertension, etc. Two most important biomarkers to measure arsenic intake in a human body are arsenic concentration in urine and hair. The primary interest of this paper is the association between skin lesion and arsenic concentration in hair for participants with chronic arsenic exposure from West Bengal, India, using bivariate regression model based on copula function. The result showed participants with high arsenic concentration in hair had higher incidence of developing skin lesion. Arsenic concentration in hair was significantly higher for the participants with an arsenic concentration in water > 10 mg/L.
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