Related Experiment Video
Updated: Feb 12, 2026

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
Choroidal osteoma in a preterm infant
Yakup Aksoy1, Yavuz Çakir1, Sükrü Sevinçli1
1Department of Ophthalmology, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey.
Insights
Choroidal osteoma, a rare bone tumor in the eye, was found in a 4-week-old premature infant. This case highlights that choroidal osteoma can occur even in newborns, challenging previous age assumptions.
Area of Science:
- Ophthalmology
- Oncology
Background:
- Choroidal osteoma (CO) is a rare, benign intraocular tumor composed of mature bone.
- Typically observed in young adult females, CO presents as a yellowish-white or orange choroidal mass.
Observation:
- A 4-week-old premature infant presented with a choroidal osteoma in the left eye.
- The tumor was incidentally detected during a routine examination for retinopathy of prematurity.
Findings:
- This represents the youngest reported case of choroidal osteoma to date.
- The presence of CO in such a young infant suggests the condition can manifest neonatally.
Implications:
- This case expands the known age range for choroidal osteoma diagnosis.
- Early detection protocols may need to consider CO in premature infants, even when screened for other conditions.
Abstract:
Choroidal osteoma (CO) is a rare, benign, and usually unilateral intraocular tumor composed of mature bone affecting the choroid. It appears as slightly elevated, yellowish-white, or orange choroidal mass with well-defined borders. It is commonly encountered in young female adults. Here, we report findings of a 4-week-old premature baby with CO in her left eye which was detected during a routine examination for "retinopathy of prematurity." We believe that this case is the youngest patient reported with CO which showing that this pathology can be encountered even in a newborn.
Related Concept Videos
Drug Dosing: Infants and Children
Theory of Romantic Attachment in Adulthood

