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Presumably contaminated intravenous infusion-induced Aspergillus terreus endogenous endophthalmitis presenting with

Mohit Dogra1, Madhuri Akella1, Mangat R Dogra1

  • 1Advanced Eye Centre, PGIMER, Chandigarh, India.

Indian Journal of Ophthalmology
|March 28, 2018
PubMed

Insights

A rare case of Aspergillus endophthalmitis occurred in an immunocompetent man after intravenous fluid infusion. Prompt treatment resolved inflammation but resulted in vision loss due to scarring.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Mycology

Background:

  • Endogenous endophthalmitis is a severe intraocular infection.
  • Fungal endophthalmitis is uncommon, particularly in immunocompetent individuals.

Observation:

  • A 36-year-old immunocompetent male presented with endogenous endophthalmitis.
  • The condition developed one week post-intravenous fluid infusion in a rural setting.
  • Clinical presentation included a large submacular abscess and posterior hypopyon.

Findings:

  • Urgent vitrectomy was performed.
  • Fungal culture identified Aspergillus terreus.
  • Treatment involved intravitreal and oral antifungal agents.
  • Inflammation resolved with satisfactory anatomical outcome.
  • Submacular scarring led to poor visual outcome.

Implications:

  • Intravenous fluid infusion can be a risk factor for endogenous fungal endophthalmitis.
  • Early diagnosis and aggressive management are crucial for anatomical preservation.
  • Submacular scarring remains a significant challenge for visual recovery in fungal endophthalmitis.
Keywords:
Aspergillus terreusendogenous endophthalmitisposterior hypopyon

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