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Updated: Feb 12, 2026

Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel
Published on: September 8, 2017
[Atypical Hemolitic Uremic Syndrome after administration of Docetaxel]
Alessandro Francesco Colombo1, Rosalia Boito1, Francesca Bova1
1U.O. Nefrologia e Dialisi, P.O. "San Giovanni di Dio" Crotone.
Abstract:
The purpose of this study is to describe the clinical case of a patient suffering from a gland carcinoma with bilateral inguinal and pelvic lymph node metastases in treatment with weekly administrations of Docetaxel. After two therapy cycles, the patient developed an atypical uremic hemolytic Syndrome (SEUa), treated with infusions of frozen fresh plasma, hemodialysis, and antibiotics. Because of a severe septic secondary complication on an extensive lymph node abscess, the administration of Eculizumab was not possible. The patient survived the mentioned Syndrome and is currently in periodic dialysis treatment.
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