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Sources of rats free of latent Pneumocystis carinii
M S Bartlett1, M M Durkin, M A Jay
1Department of Pathology, Indiana University School of Medicine, Indianapolis 46223.
Journal of Clinical Microbiology
|September 1, 1987
Abstract:
Two sources of rats free of latent Pneumocystis carinii are described. First, rats from a virus-free colony failed to develop infection after 8 weeks of immune suppression unless they were housed with previously infected rats. Second, pregnant rats (non-virus free) received trimethoprim-sulfamethoxazole from day 10 of gestation until the pups were weaned. Pups raised in filter-topped cages and immunosuppressed for 8 weeks were free of P. carinii infection.