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Updated: Feb 12, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
Published on: August 6, 2021
Modeling the effects of parameter optimization on three bioretention tanks using the HYDRUS-1D model
Jiake Li1, Ruisong Zhao1, Yajiao Li2
1State Key Laboratory of Eco-hydraulics in Northwest Arid Region of China, Xi'an University of Technology, Xi'an 710048, China.
Abstract:
The operation effects of bioretention on different tanks were investigated through tests and simulations. Three layered bioretention tanks, namely, #1, #2, and #3, were selected for intermittent operation tests. The artificial filler layers of the tanks consisted of mixed fillers of fly ash and sand, blast furnace slag, and planting soil. Models were established by using HYDRUS-1D software based on test results. The sensitivity of model parameters was analyzed through Morris screening method. Results showed that return period, thickness of media layer, and solute concentration in the liquid phase were the parameters that significantly influenced the operation effects. The Nash-Sutcliffe efficiency coefficients of the models were greater than 0.85. The simulation results showed that the reduction effects at different inflow loads were better under low loads than under high loads. The comprehensive reduction rate of pollutant load was 5.22% less under high concentrations than under low concentrations. The comprehensive reduction rates of water and pollutant loads were 35.97% and 20.68% greater, correspondingly, in the 1 year return period than in the 10 year return period. The artificial fillers comprising a mixture of fly ash and sand also showed the optimal reduction effects, with comprehensive reduction rates of 69.33% and 83.08% for water and pollutant load, respectively. The reduction effects of water and pollutants for the #1 tank presented an upward trend, whereas those for the #2 tank showed a downward trend given an increase in planting soil thickness. An increase in media thickness enhanced the reduction effects. The media with 60 cm thickness demonstrated the optimal effect.
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