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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
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Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma-II: Pathophysiology and Classification01:26

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
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Asthma-IV: Nursing Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Protein Biomarkers in Asthma.

Alexander V Karaulov1,2, Victoria Garib2,3, Firuz Garib1,4,5

  • 1Department of Clinical Immunology and Allergy, Sechenov First Moscow State Medical University, Moscow, Russian Federation.

International Archives of Allergy and Immunology
|March 28, 2018
PubMed
Summary

New protein biomarkers may help personalize asthma treatment. Identifying specific asthma types through biomarkers allows for targeted therapies beyond traditional steroids and bronchodilators, improving patient outcomes.

Keywords:
AllergyAsthmaBiomarkersMolecular allergology

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Area of Science:

  • Pulmonology
  • Biochemistry
  • Immunology

Background:

  • Asthma is a chronic respiratory disease with diverse triggers.
  • Current asthma management relies on a generalized approach using bronchodilators and steroids.
  • Emerging targeted therapies necessitate better methods for classifying asthma subtypes.

Purpose of the Study:

  • To review protein biomarkers for asthma.
  • To explore how these biomarkers can differentiate asthma phenotypes.
  • To guide the selection of targeted therapies based on individual asthma mechanisms.

Main Methods:

  • Literature review of protein biomarkers in asthma.
  • Analysis of current and emerging asthma treatment strategies.
  • Discussion of biomarker utility in personalized medicine for asthma.

Main Results:

  • Several protein biomarkers are associated with different asthma pathways.
  • Biomarkers can potentially distinguish asthma subtypes responsive to targeted treatments.
  • This approach moves beyond the "one-fits-all" model.

Conclusions:

  • Protein biomarkers are crucial for advancing personalized asthma care.
  • Accurate asthma phenotyping using biomarkers will optimize targeted therapy selection.
  • This review highlights the potential of protein biomarkers in transforming asthma management.