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Pharmacogenomics in IVF: A New Era in the Concept of Personalized Medicine
Kallirhoe Kalinderi1,2, Byron Asimakopoulos3, Nikos Nikolettos4
1Department of General Biology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Abstract:
Pharmacogenomics is a promising approach in the field of individualized medicine in in vitro fertilization (IVF) treatment that aims to develop optimized pharmacotherapy depending on the genetic background of each infertile woman, thus to ensure maximum effectiveness of the medication used, with minimal side effects. The unique genetic information of each infertile woman, in combination with already known, as well as new predictors of ovarian response and the progress of pharmacoepigenomics, is anticipated to greatly benefit the process of controlled ovarian stimulation. This review analyses current data on IVF pharmacogenomics, a new approach that is gradually moving to the frontline of modern IVF treatment.
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