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How do we define and measure sarcopenia? Protocol for a systematic review.
Paulo Roberto Carvalho do Nascimento1,2, Stéphane Poitras3, Martin Bilodeau3,4,5
1School of Rehabilitation Sciences, Faculty of Health Sciences, University of Ottawa, 43 Bruyère Street, Ottawa, ON, K1N5C8, Canada. prcnascimento@yahoo.com.br.
Systematic Reviews
|March 29, 2018
Summary
Sarcopenia, an age-related muscle loss syndrome, lacks a universal definition. This review examines how sarcopenia definitions and diagnostic tools impact prevalence rates in observational studies.
Area of Science:
- Geriatrics
- Aging Research
- Muscle Physiology
Background:
- Sarcopenia is a geriatric syndrome characterized by age-related muscle mass loss.
- Increasing research focuses on sarcopenia due to its negative health impacts on the elderly.
- Discrepancies in sarcopenia definitions, emphasizing quality over quantity, hinder consensus.
Purpose of the Study:
- To systematically review observational studies on sarcopenia.
- To analyze the various definitions and diagnostic criteria used for sarcopenia.
- To investigate the influence of differing definitions and tools on sarcopenia prevalence rates.
Main Methods:
- Comprehensive literature search across multiple databases (MEDLINE, EMBASE, CINAHL, Web of Science, Google Scholar).
- Two independent reviewers assessed study eligibility and methodological quality.
- Extracted data on sarcopenia definitions, diagnostic tools, and prevalence estimates.
Main Results:
- The review will report on the most common sarcopenia definitions and assessment tools.
- Analysis will determine if variations in definitions and tools affect reported prevalence rates.
- Descriptive statistics will be employed to summarize findings.
Conclusions:
- Sarcopenia definitions and diagnostic tools significantly influence prevalence estimates.
- A consensus on a valid and practical sarcopenia definition is needed.
- Further research should focus on standardizing sarcopenia assessment.
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