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Incidence, Clinical Implications, and Predictors of Paravalvular Leak Following Transcatheter Tricuspid Valve Replacement: The TRIPLACE Registry.

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A Quick Guide to Paravalvular Leak Closure.

Sameer Gafoor1, Jennifer Franke1, Stefan Bertog1

  • 1CardioVascular Center, Frankfurt, Germany.

Interventional Cardiology (London, England)
|March 29, 2018
PubMed
Summary
This summary is machine-generated.

Paravalvular leak (PVL) is a common complication after valve replacement. This review covers diagnosing and treating PVL, including imaging, access, and device selection for aortic and mitral PVL closure.

Keywords:
aorticclosureleakmitralparavalvarparavalvar leak closureparavalvularparavalvular leak closureplugregurgitationseverevalve

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Structural Heart Disease

Background:

  • Paravalvular leak (PVL) is an under-recognized complication following valvular replacement surgery.
  • PVL can significantly impact patient outcomes and quality of life.

Purpose of the Study:

  • To provide a comprehensive overview of the diagnosis and management of paravalvular leaks.
  • To discuss current strategies for imaging, access, and device selection in PVL closure.
  • To highlight specific considerations for aortic and mitral PVL closure.

Main Methods:

  • Review of current literature and guidelines on paravalvular leak diagnosis and treatment.
  • Discussion of imaging modalities for PVL assessment (e.g., echocardiography, CT).
  • Analysis of interventional approaches, including device selection and procedural techniques for PVL closure.

Main Results:

  • PVL diagnosis relies on a combination of clinical presentation and advanced imaging techniques.
  • Transcatheter PVL closure has emerged as a viable alternative to surgical repair for select patients.
  • Successful PVL closure can lead to significant improvement in hemodynamic parameters and clinical symptoms.

Conclusions:

  • Paravalvular leak is a critical aspect of structural heart disease management post-valve replacement.
  • Timely diagnosis and appropriate treatment selection are crucial for optimal patient outcomes.
  • Interventional strategies for PVL closure offer a less invasive option with promising results.