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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...
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The nursing management of Mitral Valve Prolapse, or MVP, centers around patient education, symptom monitoring, and lifestyle modifications.Patient Education on MVP Diagnosis and Heredity: Nurses should provide comprehensive education about MVP, a condition where the mitral valve does not close appropriately during heartbeats. This education often includes the condition's pathophysiology, symptoms, and potential complications, like arrhythmias or mitral regurgitation. Though not fully...
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Related Experiment Video

Updated: Feb 12, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
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Transcatheter Mitral Valve Devices - Functional Mechanical Designs.

Chad Kliger1

  • 1Division of Structural and Congenital Heart Disease, Lenox Hill Heart and Vascular Institute - North Shore/LIJ Health System, New York, US.

Interventional Cardiology (London, England)
|March 29, 2018
PubMed
Summary

Transcatheter mitral valve therapies (TMVT) offer less invasive options for mitral regurgitation. Advancements in TMVT, including replacement and valve-in-valve procedures, show promise for high-risk patients.

Keywords:
Mitral regurgitationtranscatheter mitral valve replacementtranscatheter mitral valve therapiesvalve-in-ringvalve-in-valve

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Area of Science:

  • Cardiology
  • Biomedical Engineering
  • Interventional Cardiology

Background:

  • Mitral regurgitation is a complex cardiac disorder affecting multiple mitral valve components.
  • There is a growing demand for less invasive treatment strategies for mitral regurgitation.

Purpose of the Study:

  • To review the current landscape and evolving functional mechanical designs of transcatheter mitral valve therapies (TMVT).
  • To explore the potential of TMVT as alternatives to traditional surgical interventions.

Main Methods:

  • Systematic review of current and developing transcatheter mitral valve technologies.
  • Analysis of functional designs and early clinical data for various TMVT approaches.

Main Results:

  • Transcatheter mitral valve replacement (TMVR) preserves the native mitral apparatus and is a potential alternative treatment.
  • Transcatheter mitral valve-in-valve and valve-in-ring implantations show encouraging early results for high-risk patients.

Conclusions:

  • TMVT represents a rapidly advancing field with diverse therapeutic options for mitral regurgitation.
  • Further technological development and combination therapies may enhance TMVT efficacy and safety, offering new hope for patients unsuitable for surgery.