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Updated: Feb 12, 2026

In Vivo Model for Testing Effect of Hypoxia on Tumor Metastasis
Published on: December 9, 2016
EACR-MRS conference on Seed and Soil: In Vivo Models of Metastasis
I Teles Alves1, N Cohen2, P G Ersan3
1Department of Cell Biology and Biochemistry, Springer Science + Business Media B.V., Dordrecht, The Netherlands. ines.alves@springernature.com.
Abstract:
New experimental tools are urgently required to better understand the metastatic process. The importance of such tools is underscored by the fact that many anti-cancer therapies are generally ineffective against established metastases. This makes a major contribution to the fact that metastatic spread is responsible for over 90% of cancer patient deaths. It was therefore timely that the recent "Seed and Soil: In Vivo Models of Metastasis" conference held in Berlin, Germany (27-29 of November 2017) aimed to give an in-depth overview of the latest research models and tools for studying metastasis, and to showcase recent findings from world-leading metastasis researchers. This Meeting Report summarises the major themes of this ground-breaking conference.
Insights
Developing new experimental tools is crucial for understanding cancer metastasis, which causes over 90% of cancer deaths. This report summarizes a conference on in vivo metastasis models and research findings.
Area of Science:
- Oncology
- Cancer Research
- Translational Medicine
Background:
- Metastatic spread is responsible for over 90% of cancer patient deaths.
- Current anti-cancer therapies are often ineffective against established metastases.
- There is an urgent need for novel experimental tools to study the metastatic process.
Purpose of the Study:
- To provide an overview of the latest research models and tools for studying metastasis.
- To showcase recent findings from leading metastasis researchers.
- To summarize the major themes of the "Seed and Soil: In Vivo Models of Metastasis" conference.
Main Methods:
- The report summarizes discussions and presentations from a scientific conference.
- Focus on in vivo models of metastasis.
- Review of cutting-edge experimental tools and research findings.
Main Results:
- The conference highlighted the critical need for advanced tools to study cancer metastasis.
- Various novel in vivo models and experimental approaches were presented.
- Key findings from world-leading metastasis researchers were showcased.
Conclusions:
- Advancements in experimental tools and in vivo models are essential for understanding and combating cancer metastasis.
- The conference underscored the progress and future directions in metastasis research.
- Effective strategies against metastasis require a deeper understanding of the underlying biological processes.
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