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Contribution of the new 2012 EULAR/ACR classification criteria for the diagnosis of polymyalgia rheumatica
F Muratore1, C Salvarani, P Macchioni
1Division of Rheumatology, Azienda USL IRCCS di Reggio Emilia; University of Modena and Reggio Emilia. francesco.muratore@ausl.re.it.
Abstract:
Polymyalgia rheumatica (PMR) is one of the most common rheumatic inflammatory disorders in people aged over 50. It is characterized by aching and prolonged morning stiffness in the shoulder and pelvic girdles and neck. To date there are no specific diagnostic tests, and in clinical practice the diagnosis of PMR remains based on its characteristic clinical manifestations, laboratory evidence of systemic inflammation, rapid response to low doses of glucocorticoids and exclusion of other disorders that may present with proximal pain and stiffness. For classification purposes, several criteria have been proposed over time based on retrospective clinical series, but none have been validated and received universal acceptance. Recently, an international collaborative initiative between the EULAR and the ACR was undertaken to develop new polymyalgia rheumatica classification criteria. In this review, the provisional 2012 EULAR/ACR classification criteria will be presented and their contribution for the diagnosis of polymyalgia rheumatica will be discussed.
Insights
Polymyalgia rheumatica (PMR) is a common inflammatory disorder in those over 50. This review discusses the provisional 2012 EULAR/ACR classification criteria for diagnosing PMR, addressing the lack of specific diagnostic tests.
Area of Science:
- Rheumatology
- Clinical Immunology
Background:
- Polymyalgia rheumatica (PMR) is a prevalent rheumatic inflammatory condition affecting individuals over 50.
- Characterized by proximal muscle pain and stiffness, particularly in the shoulder and pelvic girdles and neck.
- Current diagnosis relies on clinical presentation, inflammation markers, response to corticosteroids, and exclusion of other conditions, lacking specific diagnostic tests.
Purpose of the Study:
- To present and discuss the provisional 2012 European League Against Rheumatism (EULAR) and American College of Rheumatology (ACR) classification criteria for polymyalgia rheumatica.
- To evaluate the contribution of these new criteria to the diagnosis of PMR.
Main Methods:
- Review of an international collaborative initiative to develop new classification criteria for PMR.
- Presentation and discussion of the provisional 2012 EULAR/ACR classification criteria.
Main Results:
- The development of provisional classification criteria by a joint EULAR/ACR initiative.
- These criteria aim to standardize and improve the classification of PMR.
Conclusions:
- The provisional 2012 EULAR/ACR criteria represent a significant step towards standardized PMR classification.
- Further validation and discussion are needed to assess their universal acceptance and clinical utility in diagnosing polymyalgia rheumatica.
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