Related Experiment Video
Updated: Feb 12, 2026

Post-Myocardial Infarction Heart Failure in Closed-chest Coronary Occlusion/Reperfusion Model in Göttingen Minipigs and Landrace Pigs
Published on: April 17, 2021
Coronary chronic total occlusion intervention: utility or futility
Patrick Marechal1, Laurent Davin1, Olivier Gach1
1a GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman , University of Liège Hospital , Liège , Belgium.
Percutaneous coronary intervention for chronic total occlusions (CTO) is underutilized but improves patient outcomes. Advances in techniques and operator experience have made CTO angioplasty safer and more effective.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Chronic total occlusions (CTO) affect a significant percentage of patients undergoing coronary angiography but are infrequently treated with percutaneous coronary intervention (PCI).
- Despite underutilization, successful CTO revascularization is associated with improved symptoms, quality of life, and long-term survival.
Purpose of the Study:
- This review focuses on the clinical benefits of CTO revascularization.
- It also addresses appropriate patient selection for these complex procedures.
Main Methods:
- Review of current evidence on CTO angioplasty.
- Analysis of advancements in tools, techniques, and operator experience.
Main Results:
- Successful CTO angioplasty significantly enhances patient symptoms, quality of life, and survival rates.
- Improvements in specialized techniques and increased operator expertise have led to success and complication rates comparable to non-CTO angioplasty.
Conclusions:
- CTO revascularization offers substantial clinical benefits for selected patients.
- The increasing safety and efficacy of CTO PCI support its broader consideration in treatment strategies.
Related Concept Videos
Nursing Interventions I: Taxonomy of Nursing Interventions
A nursing intervention is a treatment or action based on scientific concepts and knowledge from the nursing, behavioral, and physical sciences. Identifying and prioritizing nursing interventions based on the desired outcome...
Nursing Interventions II: Selecting and Classifying the Nursing Interventions
Coronary Circulation
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Community Based Intervention
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...
Operant Conditioning Intervention
In operant conditioning, behaviors that are...
Total Voids in Concrete

