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Risk Factor of Mortality in Indonesian Children with Cerebral Palsy
Indra Gunawan Prastiya1, Vitria Prasetyo Risky1, Irmawati Mira1
1Department of Child Health, Airlangga University College of Medicine, Dr Soetomo Hospital.
Insights
Pneumonia, acute kidney injury, and severe GMFCS levels are key mortality risk factors in Indonesian children with cerebral palsy (CP). Understanding these factors can improve care for children with CP.
Area of Science:
- Pediatrics
- Neurology
- Public Health
Background:
- Cerebral palsy (CP) is associated with reduced life expectancy.
- Identifying mortality risk factors in children with CP is crucial for targeted interventions.
Purpose of the Study:
- To investigate the risk factors associated with mortality in Indonesian children diagnosed with cerebral palsy.
Main Methods:
- An observational analytic study utilized medical records of hospitalized children with CP aged 6 months to 14 years.
- Data from January 2014 to December 2016 at Dr. Soetomo Hospital, Surabaya, Indonesia, were analyzed.
- Logistic regression was employed to identify significant risk factors for mortality.
Main Results:
- Out of 55 children with CP, 12 (21.8%) died during the study period.
- Pneumonia was the most common cause of death (OR=5.185).
- Significant mortality risk factors included acute kidney injury (AKI) (OR=3.333) and Gross Motor Functioning Classification System (GMFCS) level greater than IV (OR=1.480).
Conclusions:
- Pneumonia, AKI, and severe GMFCS levels (greater than IV) are identified as significant risk factors for mortality in children with CP.
- These findings highlight critical areas for clinical attention and management strategies in pediatric CP care.
Objective:
Individuals with CP have a lower life expectancy than the general population. The objective of the study is to investigate the risk factor of mortality in Indonesian children with CP.
Methods:
An observational analytic study was conducted using medical records at pediatric ward Dr. Soetomo Hospital, Surabaya, Indonesia, from January 2014 to December 2016. Inclusion criteria was all of CP patients in that were hospitalized from 6 months to 14 year of age. Mortality information was obtained from annual computer and matched against the subjects with CP on the basis of name, date of birth, type of disability, degree of disability, nutritional status and the outcomes. Risk factors were counted using logistic regression.
Result:
Fifty five children were enrolled. The outcome revaled 12 patients (21.8%) were death. Pneumonia was the most common underlying disease cause of death (OR=5.185;95% CI 1.249 to 21.520;Psize 8 < 0.007). Other risk factors of mortality that significant were acute kidney injury (AKI) (OR=3.333;95% CI 1.317 to 8.436;Psize 8 < 0.03). and Gross Motor Functioning Classification System (GMFCS) more than level IV (OR=1.480;95% CI 1.184 to 1.850;Psize 8 < 0.006).
Conclusion:
Pneumonia, AKI and severe GMFCS level were risk factors of death in patients with CP. J. Med. Invest. 65:18-20, February, 2018.
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