Related Experiment Video
Updated: Feb 12, 2026

Simultaneous Multicolor Imaging of Biological Structures with Fluorescence Photoactivation Localization Microscopy
Published on: December 9, 2013
Multicolor GLUT5-permeable fluorescent probes for fructose transport analysis
V V Begoyan1, Ł J Weseliński, S Xia
1Department of Chemistry, Michigan Technological University, 1400 Townsend Drive, Houghton, Michigan 49331, USA. mtanasov@mtu.edu.
Abstract:
The specificity of carbohydrate transporters towards their substrates poses a significant challenge for the development of molecular probes to monitor sugar uptake in cells for biochemical and biomedical applications. Herein we report a new set of coumarin-based fluorescent sugar conjugates applicable for the analysis of fructose uptake due to their free passage through the fructose-specific transporter GLUT5. The reported probes cover a broad range of the fluorescence spectrum providing essential tools for the evaluation of fructose transport capacity in live cells.
Related Concept Videos
Short-distance Transport of Resources
Facilitated Transport
Permeability of Concrete
Primary Active Transport
Secondary Active Transport
Regulated mRNA Transport

