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Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications
Published on: June 23, 2016
Colorimetric aggregation based cadmium(II) assay by using triangular silver nanoplates functionalized with
Yudong Tian1, Qingyun Liu2, Yunfei Jiao1
1Department of Chemistry, Capital Normal University, Beijing, 100048, China.
Abstract:
A colorimetric method is described for sensitive and low-cost detection of Cd(II). It is based on the use of triangular silver nanoplates (tri-AgNPs) modified with 1-amino-2-naphthol-4-sulfonate (ANS) acting as a colorimetric probe. ANS is first linked to the tri-AgNPs via electrostatic interaction of the sulfo groups. In the absence of analyte, ANS on the surface of tri-AgNPs protects them from aggregation. In the presence of Cd(II), the tri-AgNPs aggregate due to the interaction between ANS and Cd(II). This results in a distinct color change from blue (absorption peak at 710 nm) to green (peak at 770 nm). UV-vis spectrometry and image analyses demonstrate that this method exhibits selective and sensitive colorimetric response to Cd(II). The color change can be easily detected with bare eyes. Response is linear in the 30 to 70 μM concentration range, and the detection limit is 30 nM. Graphical abstract A colorimetric method for sensitive, and low-cost detection of Cd(II) based on the use of tri-AgNPs modified with ANS acting as a colorimetric probe was presented.
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