Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Longitudinal Studies01:26

Longitudinal Studies

537
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
537
Longitudinal Research02:20

Longitudinal Research

13.5K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
13.5K
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

406
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
406
G-protein Coupled Receptors01:21

G-protein Coupled Receptors

132.2K
G-protein coupled receptors are ligand binding receptors that indirectly affect changes in the cell. The actual receptor is a single polypeptide that transverses the cell membrane seven times creating intracellular and extracellular loops. The extracellular loops create a ligand specific pocket which binds to neurotransmitters or hormones. The intracellular loops holds onto the G-protein.
132.2K
Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)01:20

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

1.7K
Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others.
The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...
1.7K
Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)01:22

Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)

1.5K
Vicinal or three-bond coupling is commonly observed between protons attached to adjacent carbons. Here, nuclear spin information is primarily transferred via electron spin interactions between adjacent C‑H bond orbitals. This generally favors the antiparallel arrangement of spins, so 3J values are usually positive.
The extent of coupling depends on the C‑C bond length, the two H‑C‑C angles, any electron-withdrawing substituents, and the dihedral angle between the involved orbitals. The...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postmyocardial infarction ventricular septal defect outcomes: Partial versus full presurgical hemodynamic support.

JTCVS open·2026
Same author

Impact of aortic root surgery during transcatheter aortic valve explant.

JTCVS structural and endovascular·2026
Same author

Iliac artery involvement determines optimal therapy in acute uncomplicated type B aortic dissection.

JTCVS structural and endovascular·2026
Same author

Endovascular arch repair using a novel single branch arch stent graft: 30-Day results from the chronic dissection arm of the NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness investigational device exemption study.

JTCVS structural and endovascular·2026
Same author

Standardized End Point Definitions for Clinical Trials in Thoracic Aortic Repair: A Consensus Report From the ARCH-Academic Research Consortium.

Circulation·2026
Same author

Aortic stiffening after thoracic aortic stent grafting: A multi-patient specific computational study.

Computer methods and programs in biomedicine·2026

Related Experiment Video

Updated: Feb 12, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

1.0K

Coupled Morphological-Hemodynamic Computational Analysis of Type B Aortic Dissection: A Longitudinal Study.

Huijuan Xu1,2, Marina Piccinelli3, Bradley G Leshnower4

  • 1The George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, USA. hxu72@gatech.edu.

Annals of Biomedical Engineering
|March 30, 2018
PubMed
Summary

Computational fluid dynamics (CFD) simulations reveal hemodynamic factors influencing type B aortic dissection (TBAD) progression. This study correlates blood flow patterns with aortic changes, potentially predicting late complications in TBAD patients.

Keywords:
Aortic dissectionComputational fluid dynamicsLarge eddy simulationPoint set registration

More Related Videos

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

707
Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
08:12

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS

Published on: November 26, 2018

10.6K

Related Experiment Videos

Last Updated: Feb 12, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

1.0K
A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis
09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

707
Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
08:12

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS

Published on: November 26, 2018

10.6K

Area of Science:

  • Cardiovascular Science
  • Biomedical Engineering
  • Medical Imaging

Background:

  • Type B aortic dissection (TBAD) can lead to progressive false lumen aneurysmal degeneration.
  • Understanding the multi-factorial etiology of TBAD progression is crucial for patient management.

Purpose of the Study:

  • To investigate the role of patient-specific computational fluid dynamics (CFD) in understanding TBAD progression.
  • To correlate hemodynamic parameters with the evolution of the false lumen in a longitudinal TBAD case.

Main Methods:

  • Longitudinal study of a TBAD patient with reconstructed aortic geometries from 2006 and 2010.
  • Application of registration algorithms to quantify false lumen evolution.
  • CFD simulations using large eddy simulation (LES) to compute hemodynamic indexes like wall shear stress (WSS) and relative residence time (RRT).

Main Results:

  • Quantified the temporal evolution of the false lumen using registration algorithms.
  • Computed hemodynamic indexes, including WSS and RRT, via CFD simulations.
  • Discussed correlations between hemodynamic factors and false lumen changes over time.

Conclusions:

  • Patient-specific CFD simulations offer insights into TBAD progression.
  • This methodology may help predict late complications in patients with initially uncomplicated TBAD.
  • Further validation on larger cohorts is needed to establish predictive capabilities.