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Updated: Feb 12, 2026

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
Deviations from Typical Developmental Trajectories Detectable at 9 Months of Age in Low Risk Children Later Diagnosed
Michael Davidovitch1, Nataly Stein2, Gideon Koren3,4
1Department of Child Development, Medical Division, Maccabi Healthcare Services, 27 Hamered St., 6812509, Tel Aviv, Israel. davidom@netvision.net.il.
Insights
Autism Spectrum Disorder (ASD) may be detected by 9 months of age. Early milestone delays in communication and motor skills during well-child checkups can signal the need for further evaluation and intervention.
Area of Science:
- Developmental Pediatrics
- Neurodevelopmental Disorders
- Early Childhood Intervention
Background:
- Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition.
- Early identification and intervention are crucial for improving outcomes in children with ASD.
- Routine Well Care checkups offer opportunities for developmental screening.
Purpose of the Study:
- To track the developmental trajectory of infants later diagnosed with ASD during the first 24 months of life.
- To identify early deviations in developmental milestones during routine Well Care checkups.
- To compare developmental achievements of infants with ASD to typically developing children and those with other developmental impairments.
Main Methods:
- Longitudinal study of 335 low-risk infants.
- Tracking developmental milestones during the first 24 months of life.
- Comparison with typically developing children and children with non-autistic developmental impairments.
Main Results:
- Infants later diagnosed with ASD showed normal milestone acquisition in the first 6 months.
- By 9 months of age, infants with ASD began to show delays in language/communication and motor skills.
- These delays were significant when compared to both typically developing and non-autistic delayed children.
Conclusions:
- Routine Well Care checkups can be effective in identifying early signs of developmental delay in infants.
- Failure to achieve specific milestones by 9 months may indicate a need for further ASD evaluation.
- Earlier detection through regular checkups can facilitate timely referral for diagnosis and treatment.
Abstract:
This study was designed to track the developmental trajectory, during the first 24 months of life, of 335 low-risk infants later diagnosed with Autism Spectrum Disorder and identify early deviations observed in routine Well Care checkups. We compared their achievements to typically developing children and to children later diagnosed with non-autistic developmental impairments. The results show that in the first 6 months, the children with autism showed normal acquisition of milestones, whereas by 9 months of age they began to fail the language/communication, as well as motor items when compared to typical and delayed non-autistic children. Regular check-up visits may be useful in detecting early failure in achieving milestones, leading to earlier referral for further evaluation and treatment.
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