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Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction
Published on: October 14, 2016
CVIT expert consensus document on primary percutaneous coronary intervention (PCI) for acute myocardial infarction
Yukio Ozaki1, Yuki Katagiri2, Yoshinobu Onuma3,4
1Department of Cardiology, Fujita Health University School of Medicine, Toyoake, Japan. ozakiyuk@fujita-hu.ac.jp.
Insights
Primary percutaneous coronary intervention (PCI) is standard care for ST-elevation myocardial infarction in Japan. This expert consensus document addresses procedural aspects of PCI, considering European guidelines and Japanese practices.
Area of Science:
- Cardiology
- Interventional Cardiology
- Acute Myocardial Infarction Management
Background:
- Primary percutaneous coronary intervention (PCI) significantly reduces mortality in ST-elevation myocardial infarction (STEMI), including cases with cardiogenic shock.
- Primary PCI is the standard of care in most Japanese institutions, despite a lack of specific procedural guidelines.
- European Society of Cardiology guidelines recommend radial access and drug-eluting stents, and complete revascularization, but direct application to Japan is challenging due to device lag and differing practices.
Framework:
- Recent European Society of Cardiology guidelines recommend radial access and drug-eluting stents (Class I) and complete revascularization (Class IIa).
- Differences in device availability, imaging modality use, and medical/mechanical support between Europe and Japan limit direct guideline application.
Implementation:
- The Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT) Task Force developed an expert consensus document.
- This document focuses on the procedural aspects of primary PCI for acute myocardial infarction.
Implications:
- The consensus aims to standardize primary PCI procedures within the Japanese healthcare system.
- It provides tailored recommendations for managing acute myocardial infarction, considering regional differences.
Abstract:
While primary percutaneous coronary intervention (PCI) has significantly contributed to improve the mortality in patients with ST segment elevation myocardial infarction even in cardiogenic shock, primary PCI is a standard of care in most of Japanese institutions. Whereas there are high numbers of available facilities providing primary PCI in Japan, there are no clear guidelines focusing on procedural aspect of the standardized care. Whilst updated guidelines for the management of acute myocardial infarction were recently published by European Society of Cardiology, the following major changes are indicated; (1) radial access and drug-eluting stent over bare metal stent were recommended as Class I indication, and (2) complete revascularization before hospital discharge (either immediate or staged) is now considered as Class IIa recommendation. Although the primary PCI is consistently recommended in recent and previous guidelines, the device lag from Europe, the frequent usage of coronary imaging modalities in Japan, and the difference in available medical therapy or mechanical support may prevent direct application of European guidelines to Japanese population. The Task Force on Primary Percutaneous Coronary Intervention of the Japanese Association of Cardiovascular Intervention and Therapeutics (CVIT) has now proposed the expert consensus document for the management of acute myocardial infarction focusing on procedural aspect of primary PCI.
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