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Updated: Feb 12, 2026

Ultrasonography of the Adult Male Urinary Tract for Urinary Functional Testing
Published on: August 14, 2019
The relationship between lower urinary tract symptoms and irritable bowel syndrome: a meta-analysis of
Zhihu Li1, Wei Huang1, Xiaoyan Wang1
1Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Introduction:
While several epidemiologic studies have investigated the relationship between lower urinary tract symptoms (LUTS) and irritable bowel syndrome (IBS), it remains unclear. To investigate the relationship between IBS and LUTS, a systematic review and meta-analysis of cross-sectional studies was carried out.
Evidence Acquisition:
Online databases were searched up to December 1st, 2017 for cross-sectional studies that evaluated the association between IBS and the risk of LUTS. Summary odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated.
Evidence Synthesis:
In all, 9 articles that contained 19907 participants and 2620 cases of LUTS were included in this meta-analysis. Compared with the non-IBS group, the IBS group had a higher risk of LUTS (total OR=2.11, 95% CI: 1.91-2.33, P<0.00001). Patients with IBS were more likely to have urine storage symptoms (total OR=1.80, 95% CI: 1.34-2.42, P<0.0001). Subgroup analysis by gender showed that the IBS group had a higher risk of LUTS in both men (total OR=2.17, 95% CI: 1.82-2.58, P<0.00001) and women (total OR=1.85, 95% CI: 1.57-2.17, P<0.00001).
Conclusions:
Our meta-analysis provides evidence that IBS is associated with an increased risk of LUTS in both men and women.
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