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Structural and functional aspects of metal-thiolate centres in metallothionein
1Anorganische Biochemie, Physiologisch-Chemisches Institut, Universität Tübingen, W-Germany.
Experientia. Supplementum
|January 1, 1987
Abstract:
The structural parameters of the metal thiolate binding centres in metallothionein are summarized. Regardless of biological origin there appears to be a general concept. Four thiolate sulphurs are tetrahedrally arranged around a d10 metal. One functional aspect dealing with the direct metal transfer from these clusters into the vacant metal binding sites of many a copper and/or zinc protein is shown.