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Risk Factor Analysis for Capsular Contracture: A 10-Year Sientra Study Using Round, Smooth, and Textured Implants for
M Bradley Calobrace1,2, W Grant Stevens1,2, Peter J Capizzi1,2
1Louisville and Lexington, KY; Marina Del Ray, CA; Charlotte, NC; Santa Monica, CA; and Santa Barbara, CA.
Plastic and Reconstructive Surgery
|March 30, 2018
Summary
Capsular contracture after breast augmentation is linked to implant surface, placement, and surgical factors. Identifying these risks can help reduce reoperations and improve patient outcomes in augmentation procedures.
Area of Science:
- Plastic Surgery
- Biomaterials Science
Background:
- Capsular contracture is a frequent complication after breast implant surgery.
- It is a primary reason for reoperation in augmentation patients.
- This study investigates long-term risk factors for capsular contracture.
Purpose of the Study:
- To update previous findings on risk factors for capsular contracture.
- To analyze long-term data from primary augmentation patients.
- To identify key factors influencing capsular contracture development.
Main Methods:
- Analysis of 5,122 implants in 2,565 primary augmentation patients.
- Utilized long-term data from a clinical study.
- Employed frequency and multivariate models to assess risk factors.
Main Results:
- A 10.8% Kaplan-Meier rate for capsular contracture by device over 10 years.
- Eight factors independently associated with capsular contracture identified.
- Implant surface and steroid irrigation linked to early onset contracture.
Conclusions:
- Smooth implant surfaces and smaller device sizes are risk factors.
- Subglandular placement and periareolar incisions increase risk.
- Hematoma/seroma development and antibiotic irrigation are significant factors.
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