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Fast-Track Recovery Program After Major Liver Resection: A Randomized Prospective Study.

Maria Kapritsou1, Dimitrios P Korkolis, Margarita Giannakopoulou

  • 1Maria Kapritsou, PhD, RN, is with Hellenic Anticancer Institute, "Saint Savvas" Hospital, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece. Dimitrios P. Korkolis, PhD, MD, is Consultant Surgeon, Hellenic Anticancer Institute, "Saint Savvas" Hospital, Athens, Greece. Margarita Giannakopoulou, BSc, PhD, RN, is Professor, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece. Ioannis Kaklamanos, PhD, MD, is Associate Professor, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece. Maria Konstantinou, MSc Statistician, GIS, is Statistician, GIS AUEB, Utrecht University (UU), Athens, Greece. Theodoros Katsoulas, PhD, RN, is Assistance Professor, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece. Panagiotis Kiekkas, PhD, RN, is with Department of Anesthesiology, General University Hospital of Patras, Patras, Greece. Evangelos A. Konstantinou, MSc, PhD, RN, is Professor of Nursing Anesthesiology, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece.

Gastroenterology Nursing : the Official Journal of the Society of Gastroenterology Nurses and Associates
|March 30, 2018
PubMed
Summary
This summary is machine-generated.

The fast-track (FT) recovery protocol significantly reduced postoperative complications and hospital stays for major liver resection patients compared to the conventional (CON) protocol. This enhanced recovery after surgery approach is safe and efficient.

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Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Enhanced Recovery Protocols

Background:

  • Major liver resections are complex procedures with significant perioperative morbidity.
  • Conventional recovery protocols may lead to prolonged hospital stays and higher complication rates.

Purpose of the Study:

  • To compare the efficacy of a fast-track (FT) recovery protocol versus a conventional (CON) protocol in patients undergoing major liver resection.
  • To evaluate perioperative morbidity, length of hospitalization, and readmission rates between the two protocols.

Main Methods:

  • A prospective randomized study involving 62 patients with malignant liver tumors undergoing major liver resection.
  • Patients were divided into two groups: FT protocol (n=32) and CON protocol (n=30).
  • Outcomes assessed included postoperative morbidity, readmission rates, and length of hospital stay.

Main Results:

  • The FT protocol group experienced significantly lower complication rates (25%) compared to the CON group (60%, p = .002).
  • The FT group had a substantially shorter median hospital stay (5.75 days) versus the CON group (13.5 days, p < .001).
  • Readmission rates did not differ significantly between the groups (6.25%, p = .35).

Conclusions:

  • The fast-track recovery protocol is safe and efficient for patients undergoing major liver resections.
  • FT protocol implementation leads to reduced postoperative morbidity and shorter hospitalizations.
  • Age and BMI did not impede the successful application of the FT protocol.