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Quantitative Assessment of Thyroid, Submandibular, and Parotid Glands Elasticity With Shear-Wave Elastography in
Hatice Arioz Habibi1, Emine Sebnem Memis Durmaz1, Vusale Qarayeva1
1Department of Radiology and.
Insights
Ultrasound elastography can assess tissue elasticity in children. This study establishes normal elasticity ranges for pediatric thyroid and salivary glands, showing elasticity increases with age.
Area of Science:
- Pediatric imaging
- Biomedical engineering
- Medical diagnostics
Background:
- Tissue elasticity is increasingly vital for evaluating inflammatory diseases.
- Adolescence brings significant changes to thyroid and salivary glands.
- Establishing age-specific elasticity ranges is crucial for pediatric ultrasound elastography.
Purpose of the Study:
- To determine mean elasticity ranges for pediatric thyroid, submandibular, and parotid glands.
- To investigate the correlation between age and gland elasticity in healthy children.
- To provide baseline quantitative elasticity measures for future pediatric studies.
Main Methods:
- Shear-wave elastography was used to evaluate the thyroid, submandibular, and parotid glands.
- 127 healthy volunteers (ages 3-17 years) participated in the study.
- Elasticity values were measured in kilopascals (kPa).
Main Results:
- Mean elasticity values were 14.6 ± 3.3 kPa (thyroid), 11.8 ± 2.2 kPa (submandibular), and 11.8 ± 2.6 kPa (parotid).
- A significant positive correlation was found between age and elasticity for all three glands.
- Thyroid gland elasticity showed a significant age-dependent increase, independent of weight and height.
Conclusions:
- This study provides essential baseline quantitative elasticity measures for pediatric thyroid and salivary glands.
- Age is a significant factor influencing tissue elasticity in these glands during childhood and adolescence.
- These findings support the wider application of ultrasound elastography in pediatric diagnostics.
Abstract:
Tissue elasticity is becoming a more commonly used parameter in evaluation of parenchyma in inflammatory diseases. Considering the changes in the thyroid and salivary glands with adolescence, determination of mean elasticity ranges with a function of age is necessary to apply ultrasound elastography more widely in the pediatric population.The thyroid, submandibular, and parotid glands of 127 healthy volunteers (66 males, 61 females; mean age = 10.3 ± 3.9 years; range = 3-17 years) were evaluated with shear-wave elastography.The mean elasticity values for the thyroid, submandibular, and parotid glands were 14.6 ± 3.3, 11.8 ± 2.2, and 11.8 ± 2.6 kPa, respectively. There was a significant positive correlation between age and elasticity of the thyroid, submandibular, and parotid glands. There was a significant correlation between age and elasticity value of the thyroid gland adjusted for weight and height.This study provided the baseline quantitative elasticity measures of thyroid, submandibular, and parotid glands, which would be a reference for upcoming studies. In addition, an increase in elasticity value in thyroid gland as a function of age independent of change in weight and height was demonstrated.
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