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Tumor Engraftment in a Xenograft Mouse Model of Human Mantle Cell Lymphoma
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Rituximab Maintenance Therapy After First-Line Induction Chemoimmunotherapy for Follicular Lymphoma
Talal Hilal1, Jose F Leis1, Craig B Reeder1
1Division of Hematology/Oncology, Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona.
JAMA Oncology
|March 30, 2018
Abstract
Clinical Question:
Is rituximab maintenance therapy after first-line induction chemoimmunotherapy for follicular lymphoma associated with improved outcomes?
Bottom Line:
Compared with observation, rituximab maintenance therapy prolongs progression-free survival without an improvement in overall survival or quality of life after first-line induction chemoimmunotherapy.
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