Related Experiment Video

Updated: Feb 12, 2026

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes
03:19

Author Spotlight: Studying the Impact of Maternal Dietary Deficiencies on Long-Term Offspring Health Outcomes

Published on: June 28, 2024

800

Maternal Asthma Is an Independent Risk Factor for Long-Term Respiratory Morbidity of the Offspring

E Spiegel1, I Shoham-Vardi2, A Goldbart3

  • 1Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

American Journal of Perinatology
|March 30, 2018
PubMed

Insights

Maternal bronchial asthma significantly increases offspring

Area of Science:

  • Pediatric Respiratory Medicine
  • Obstetrics and Gynecology
  • Epidemiology

Background:

  • Maternal bronchial asthma prevalence and its impact on offspring respiratory health require further investigation.
  • Understanding this association is crucial for early intervention and management strategies.

Purpose of the Study:

  • To determine if maternal bronchial asthma is a risk factor for long-term respiratory morbidity in offspring.
  • To quantify the association between maternal asthma and pediatric respiratory diseases.

Main Methods:

  • Population-based cohort study including over 250,000 deliveries.
  • Kaplan-Meier survival analysis and multivariate generalized estimating equation (GEE) logistic regression were used.
  • Exclusion of congenital malformations and multiple pregnancies.

Main Results:

  • Offspring of mothers with asthma showed a significantly higher rate of long-term respiratory morbidity (OR=1.5, 95% CI=1.3-1.7).
  • Childhood asthma incidence was notably higher in offspring exposed to maternal asthma (adjusted OR=2.5, 95% CI=1.9-3.1).
  • Maternal asthma identified as an independent risk factor for offspring's respiratory diseases (adjusted OR=1.6, 95% CI=1.4-1.9).

Conclusions:

  • Maternal bronchial asthma is an independent risk factor for long-term respiratory morbidity in children.
  • This highlights the importance of managing maternal asthma during pregnancy for offspring's respiratory well-being.
Abstract

More Related Videos

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

32.5K
In Vitro Rearing of Solitary Bees: A Tool for Assessing Larval Risk Factors08:50

In Vitro Rearing of Solitary Bees: A Tool for Assessing Larval Risk Factors

Published on: July 16, 2018

8.7K

Related Concept Videos

Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.8K
Drug Toxicity: Risk factors01:24

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...
1
Introduction to Test of Independence01:21

Introduction to Test of Independence

In statistics, the term independence means that one can directly obtain the probability of any event involving both variables by multiplying their individual probabilities. Tests of independence are chi-square tests involving the use of a contingency table of observed (data) values.
The test statistic for a test of independence is similar to that of a goodness-of-fit test:
3.0K
Hypothesis Test for Test of Independence01:16

Hypothesis Test for Test of Independence

The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
8.2K
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.4K