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Published on: October 31, 2012
Pneumatosis intestinalis after lung transplantation for pulmonary graft-versus-host disease
Kumi Mesaki1, Seiichiro Sugimoto1, Shinji Otani2
1Department of General Thoracic Surgery, Okayama University Hospital, Okayama, Japan.
Abstract:
Pneumatosis intestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). In addition to the long-term immunosuppression administered for pulmonary GVHD, the intense immunosuppression needed after LT might increase the risk of PI in lung transplant recipients after HSCT. Conservative therapy should be considered for the treatment of PI developing after LT.
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