Pelvic Artery Calcification Score Is a Marker of Vascular Calcification in Male Hemodialysis Patients

Tomohiko Matsuura1, Takaya Abe1, Mitsutaka Onoda1

  • 1Department of Urology, Iwate Medical University School of Medicine, Morioka, Japan.

Insights

Pelvic artery calcification scores (PACS) offer a novel method for evaluating vascular calcification in hemodialysis patients. This approach may overcome limitations of traditional coronary artery calcification scores in this population.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Patients undergoing hemodialysis have a high prevalence of cardiovascular disease (CVD).
  • Coronary artery calcification (CAC) scoring is crucial for CVD risk assessment but can be inaccurate in hemodialysis patients due to severe calcification.
  • A calcification evaluation method specific to hemodialysis patients is needed.

Purpose of the Study:

  • To investigate pelvic artery calcification scores (PACS) as a potential marker for vascular calcification in hemodialysis patients.
  • To compare PACS in hemodialysis patients versus controls with normal renal function.

Main Methods:

  • Utilized 64-row multi-slice CT to assess pelvic artery calcification.
  • Applied the Agatston method for calculating both coronary artery calcification scores (CACS) and PACS.
  • Compared male patients undergoing hemodialysis with male patients of normal renal function.

Main Results:

  • Hemodialysis patients showed a significantly higher incidence of pelvic artery calcification (79.7%) compared to controls (5.5%).
  • A correlation was observed between PACS and CACS, and between PACS and dialysis duration.
  • Penile artery calcification was also more prevalent in hemodialysis patients.

Conclusions:

  • Pelvic artery calcification is highly prevalent in hemodialysis patients.
  • PACS, quantifiable via the Agatston method, shows potential as a reliable vascular calcification evaluation tool for hemodialysis patients.
  • PACS may serve as a valuable alternative for assessing vascular calcification in this high-risk group.

Related Concept Videos

Hemodialysis I: Introduction01:25

Hemodialysis I: Introduction

Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
1.9K
Seedless Vascular Plants03:24

Seedless Vascular Plants

Seedless Vascular Plants Were the First Tall Plants on Earth
67.7K
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
954
Introduction to z Scores01:06

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
11.3K
Introduction to z Scores01:05

Introduction to z Scores

A z score (or standardized value) is measured in units of the standard deviation. It indicates how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a zero z score. It is important to note that the mean of the z scores is zero, and the standard deviation is one.
z scores...
1.4K
z Scores and Area Under the Curve01:17

z Scores and Area Under the Curve

z scores are the standardized values obtained after converting a normal distribution into a standard normal distribution. A z score is measured in units of the standard deviation. The z score tells you how many standard deviations the value x is above (to the right of) or below (to the left of) the mean, μ. Values of x that are larger than the mean have positive z scores, and values of x that are smaller than the mean have negative z scores. If x equals the mean, then x has a z score of...
19.6K