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Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
Five macrocyclic glycosides from Schoenoplectus tabernaemontani
Dian Peng1, Xiaolin Lin2, Lin Jiang3
1a Xiangya School of Pharmaceutical Sciences, Central South University , Changsha , China.
Abstract:
Macrocyclic glycosides with unique 22-membered dimeric lactone skeleton, are rare occurring natural products. There are only ten compounds reported so far. Herein we reported the isolation and characterisation of five macrocyclic glycosides from Schoenoplectus tabernaemontani, including three new compounds (Schoenopolide A-C, 1-3) and two known ones, Berchemolide (4) and Clemoarmanoside B (5). Their structures were established on the basis of extensive analysis of spectroscopic data. In addition, the anti-oxidative activity of Berchemolide (4) against H2O2-induced of renal tubular epithelial (HK-2) cells was also evaluated.
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